A Correspondence between Individual Differences in the Brain's Intrinsic Functional Architecture and the Content and Form of Self-Generated Thoughts

Description: To understand the relationship between self-generated mental activity and intrinsic neural fluctuations, we developed the New York Cognition Questionnaire (NYC-Q) to access the content and form of an individual's experiences during the acquisition of resting-state functional magnetic resonance imaging data. The self-report assessment and imaging data were collected as a part of the Nathan Kline Rockland Enhanced sample, which is a large-scale community sample of both phenotypic and neuroimaging data that is being openly shared as it is acquired. We decomposed NYC-Q scores using exploratory factor analysis and used these components to explore relationships between types of spontaneous thought and measures of intrinsic brain activity, specifically fractional amplitude of low frequency fluctuations, regional homogeneity, and degree centrality.

Related article: http://doi.org/10.1371/journal.pone.0097176