Intranasal oxytocin alters amygdala-temporal resting-state functional connectivity in body dysmorphic disorder: A double-blind placebo-controlled randomized trial

Description: The present study assessed the effects of intranasal oxytocin on the neural basis of processing emotional faces in patients with body dysmorphic disorder (BDD). Twenty BDD patients and 22 matched healthy control participants participated in a randomized, double-blind placebo-controlled within-subject functional magnetic resonance imaging study. Following acute intranasal OXT (24 IU) or placebo administration, we examined group and OXT related differences in task-based amygdala activation and related functional connectivity in response to an emotional face-matching task of fearful, angry, disgusted, sad, surprised and happy faces.

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Add DateMarch 24, 2018, 3:50 a.m.
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Related article DOI10.1016/j.psyneuen.2019.05.022
Related article authorsSally A. Grace, Izelle Labuschagne, David J. Castle and Susan L. Rossell
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