Supra-Additive Effects of Combining Fat and Carbohydrate on Food Reward

Description: Post-ingestive signals conveying information about the nutritive properties of food are critical for regulating ingestive behavior. Here, using an auction task concomitant to fMRI scanning, we demonstrate that participants are willing to pay more for fat+carbohydrate compared to equally familiar, liked, and caloric fat or carbohydrate foods and that this potentiated reward is associated with response in areas critical for reward valuation including the dorsal striatum and mediodorsal thalamus. We also show that individuals are better able to estimate the energy density of fat compared to carbohydrate and fat+carbohydrate foods; an effect associated with functional connectivity between visual (fusiform gyrus) and valuation (vmPFC) areas. These results provide the first demonstration that foods high in fat and carbohydrate are, calorie for calorie, valued more than foods containing only fat or carbohydrate and that this effect is associated with greater recruitment of central reward circuits.

Related article:

View ID Name Type
Field Value
Compact Identifier
Add DateApril 30, 2018, 4:51 p.m.
Uploaded byadifeliceantonio
Related article DOI10.1016/j.cmet.2018.05.018
Related article authorsAlexandra G. DiFeliceantonio, GĂ©raldine Coppin, Lionel Rigoux, Sharmili Edwin Thanarajah, Alain Dagher, Marc Tittgemeyer and Dana M. Small
Citation guidelines

If you use the data from this collection please include the following persistent identifier in the text of your manuscript:

This will help to track the use of this data in the literature. In addition, consider also citing the paper related to this collection.