Supra-Additive Effects of Combining Fat and Carbohydrate on Food Reward

Contributed by adifeliceantonio

If you use data from this collection please cite:
http://doi.org/10.1016/j.cmet.2018.05.018

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AuthorsAlexandra G. DiFeliceantonio, GĂ©raldine Coppin, Lionel Rigoux, Sharmili Edwin Thanarajah, Alain Dagher, Marc Tittgemeyer and Dana M. Small
DescriptionPost-ingestive signals conveying information about the nutritive properties of food are critical for regulating ingestive behavior. Here, using an auction task concomitant to fMRI scanning, we demonstrate that participants are willing to pay more for fat+carbohydrate compared to equally familiar, liked, and caloric fat or carbohydrate foods and that this potentiated reward is associated with response in areas critical for reward valuation including the dorsal striatum and mediodorsal thalamus. We also show that individuals are better able to estimate the energy density of fat compared to carbohydrate and fat+carbohydrate foods; an effect associated with functional connectivity between visual (fusiform gyrus) and valuation (vmPFC) areas. These results provide the first demonstration that foods high in fat and carbohydrate are, calorie for calorie, valued more than foods containing only fat or carbohydrate and that this effect is associated with greater recruitment of central reward circuits.
JournalCell Metabolism
Contributors
DOI10.1016/j.cmet.2018.05.018
Field StrengthNone
id3787
Add DateApril 30, 2018, 4:51 p.m.