Learning of distant state predictions by the orbitofrontal cortex in humans
Description: [Wimmer & Büchel (2019) Nature Comm] Group-level SPM maps from the primary contrasts. Here, we show using fMRI that while participants learned to find rewards in multiple different Y-maze environments, hippocampal activity was highest during initial exposure and then decayed across the remaining repetitions of each maze, consistent with a role in rapid encoding. Multivariate patterns in the OFC-VPFC came to represent predictive information about upcoming states approximately 30 s in the future.
Related article: http://doi.org/10.1038/s41467-019-10597-z
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