Effect of Risperidone Monotherapy on Dynamic Functional Connectivity of Insular Subdivisions in Treatment-Naive, First-Episode Schizophrenia
Description: Longitudinal study of the dFC of insular subdivisions was conducted in 42 treatment-naive first-episode patients with schizophrenia at baseline and after 8 weeks of risperidone treatment based on resting-state functional magnetic resonance image (fMRI). We first compared treatment-naive first-episode schizophrenia patients with healthy controls to investigate the abnormal patterns of the dFC of insular subdivisions. We then conducted a longitudinal study to determine whether the dFC of insular subdivisions was modified after antipsychotic treatment by comparing schizophrenia patients at baseline and after 8 week treatment.
Related article: http://doi.org/10.1093/schbul/sbz087
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