Non-selective response inhibition in Go/NoGo task: Bayesian analysis of fMRI data

Description: According to the hypothesis of non-selective inhibition, when the context is uncertain (equal probability of NoGo and Go stimuli), the need for response inhibition arises for both NoGo and Go trials. Twenty healthy participants performed a cued Go/NoGo task with an equiprobable presentation of Go and NoGo stimuli. 1) To reveal brain areas previously associated with response inhibition in similar experimental conditions, we performed a meta-analysis of fMRI studies using equal probability Go/NoGo tasks. 2) Bayesian analysis of our fMRI data has made it possible to define the brain structures, wherein practical equivalence of neuronal activity was observed in equiprobable Go and NoGo trials. 3) We observed overlap between response inhibition areas and areas demonstrating practical equivalence of neuronal activity located in the right dorsolateral prefrontal cortex, inferior parietal lobule, premotor cortex, and left inferior frontal gyrus. Thus, obtained results favour the existence of non-selective response inhibition, which can act in settings of context uncertainty, modelled by the equal probability of Go and NoGo stimuli.

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Add DateOct. 22, 2019, 4:31 p.m.
Uploaded byMasharipov
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