Progressive pathology is functionally linked to the domains of language and emotion: meta-analysis of brain structure changes in schizophrenia patients

Description: We conducted a quantitative coordinate-based meta-analysis in patients with schizophrenia, assessing regions of brain structure changes, physiological functions and the correlation of their likelihood with disease duration. In patients, four clusters showed convergent grey matter (GM) reduction, while one cluster indicated higher GM values. Voxel-wise analysis revealed a correlation between GM reduction and disease duration in the left anterior insula. Functional characterisation revealed association with reward, affective processing and language functions. This dataset was automatically imported from the ANIMA <> database. Version: 1

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Add DateSept. 16, 2015, 7:36 p.m.
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Related article DOI10.1007/s00406-011-0249-8
Related article authorsThomas Nickl-Jockschat, Frank Schneider, Alena D. Pagel, Angie R. Laird, Peter T. Fox and Simon B. Eickhoff
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