Reproducibility and Temporal Structure in Weekly Resting-State fMRI over a Period of 3.5 Years

Description: We have acquired a longitudinal single-subject dataset of a healthy volunteer (40 years of age at time of initial scan; male). A total of 158 sessions of MRI data was acquired on a weekly basis, over a span of 185 weeks (a little over 3 years). The subject was scanned on a 3T Philips Achieva scanner (Philips HealthCare, Best, Netherlands). Rs-fMRI data of the subject was acquired using a multi-slice SENSE-EPI pulse sequence with TR/TE = 2000/30 ms, SENSE factor = 2, flip angle = 75°, 37 axial slices, nominal resolution = 3x3x3 mm3, 1 mm gap, 16 channel neuro-vascular coil, number of dynamics (frames) per run = 200. The rs-fMRI scans were always acquired after the T1w scans, to allow participants to get acclimated to the noise and environment inside the scanner. The subject was instructed to stay as still as possible with his eyes closed during the entire scan, and no other instruction was provided. This is intended to be a resource for statisticians and imaging scientists to be able to quantify the intra-subject inter-session reproducibility of their image analysis methods using data available from a generic 7 min session at 3T. The full dataset is available through NITRC. Here, the resulting aggregate maps from the independent component analysis (ICA) are uploaded.

Related article: http://doi.org/10.1371/journal.pone.0140134