ROI of vmPFC

Contributed by MareikeM on Feb. 19, 2016

Collection: REM Sleep Is Causal to Successful Consolidation of Dangerous and Safety Stimuli and Reduces Return of Fear after Extinction

Description: For this region of interest of the vmPFC we computed an activation likelihood estimation (ALE) probability map (Eickhoff et al., 2009, 2012; Turkeltaub et al., 2002; p<0.05, cluster-level inference with cluster forming threshold p<0.001) on coordinates derived from 13 reports with 15 extinction recall studies (Garfinkel et al., 2014; Feng et al., 2014; Hermann et al., 2014; Kalisch, 2006; Milad et al., 2007, 2009; Pejic et al., 2013; Phelps et al., 2004; Rougemont-Bücking et al., 2011; Spoormaker et al., 2010, 2012; Menz et al., 2013; Lonsdorf et al., 2014) and 300 healthy human subjects (only or in comparison to patients) that reported whole brain activation at an uncorrected threshold of p < 0.001. After cluster-level inference (p<0.05; p<0.001 cluster-forming value) ALE results showed a large vmPFC cluster (125 voxels, 1000mm3), centered at x,y,z=0,36,-15 (ALEMAX=0.0169). The map provided here is registered to Colin27_T1_seg_MNI_2x2x2.nii (brainmap.org). For the publication we warped the map (with DARTEL) to vbm12 template space.