Figure 1

Contributed by ANIMA on Aug. 22, 2016

Collection: Brain structure anomalies in autism spectrum disorder-a meta-analysis of VBM studies using anatomic likelihood estimation

Description: Significant clusters of convergence obtained by ALE-based analysis indicating locations in the lateral occipital lobe, the pericentral region, the medial temporal lobe, the basal ganglia and proximate to the right parietal operculum. Both foci indicating gray and white matter changes were included in this model. Since disturbances in brain growth trajectories were discussed as a key pathophysiological feature in ASD, we integrated both foci reporting increases and decreases of gray matter (GM) or white matter (WM) in our analysis. Thus, the depicted clusters indicate brain regions consistently altered in ASD patients.

Tags: anima meta-analysis brain structure anatomic-likelihood estimation cytoarchitectural probabilistic mapping autism spectrum disorder

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