Figure 4: Old-Young nPPI-DMN: (F Rec > F Def) > (C Rec > C Def) (H2.2)

Contributed by david.v.smith on July 21, 2021

Collection: Age-Related Differences in Ventral Striatal and Default Mode Network Function During Reciprocated Trust

Description: Figure 4: Older Adults Show Enhanced DMN-TPJ Connectivity as a Function of Social Closeness (A) We used a network psychophysiological interaction (nPPI) analysis with the default mode network (DMN) as a seed. We examined connectivity with DMN as a function of age differences and social closeness (friend > computer) during the outcome phase (reciprocate > defect). This double subtraction analysis [(friend reciprocate > friend defect) > (computer reciprocate > computer defect)] indicated that DMN connectivity with the temporal-parietal junction (TPJ) was enhanced in older adults. (B) For illustrative purposes, we extracted the parameter estimates within this TPJ region. We note that Z statistic images were thresholded parametrically (Gaussian Random Field Theory) using clusters determined by Z>3.1 and a (corrected) cluster significance threshold of P=0.05.

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