Altered amplitude of low-frequency fluctuations in inactive patients with non-neuropsychiatric systemic lupus erythematosus

Description: The attached documents are the data of “Altered amplitude of low-frequency fluctuations in inactive patients with non-neuropsychiatric systemic lupus erythematosus”. We compared the head motions of the two groups of subjects using mean FD Jenkinson. The results showed that there was no significant difference between two groups in head motions (P = 0.869). Two patients and three controls with motion (Mean FD Jenkinson) greater than 2*SD above the group mean motion (threshold: 0.137mm) were excluded considering the standard of head motion. The data “P011”, “P030”, “C014”, “C016”, “C019” were excluded for head motion. And we regressing out nuisance variables, including Friston-24 head motion parameters, the cerebrospinal flow signals and whiter matter signals after head motion correction. Multiple comparisons were performed by 3dClusterSim using AFNI 18.0.27. The FWHM were estimated by each residual map of statistical analysis (ALFF = [7.5, 7.7, 7.4], fALFF = [7.1, 7.3, 6.5]). ALFF and fALFF analyses were performed using the RESTplus V1.2. After preprocessing, the time series of each voxel was transformed to frequency domain by fast Fourier transform (FFT), and the power spectrum was obtained. The square root was calculated at each frequency of the power spectrum. The averaged square root across 0.01-0.08 Hz was taken as ALFF of each voxel. The ratio of the sum of amplitude within the 0.01-0.08 Hz to that of the whole frequency band was calculated as fALFF. For standardization, the fALFF value of each voxel was divided by the mean fALFF within the brain mask.

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Compact Identifierhttps://identifiers.org/neurovault.collection:4814
Add DateFeb. 8, 2019, 12:22 p.m.
Uploaded byyangxuyan@163.com
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