Description: We investigated how developmental improvements in motor response cancellation performance, measured with the stop-signal reaction time (SSRT), were reflected by maturational changes in the white matter microstructure of the underlying fronto-basal ganglia "stopping" network. Eighty-eight typically-developing children and adolescents, aged 7-19 years, were longitudinally assessed with the stop-signal task (SST) and diffusion tensor imaging (DTI) of the brain over a period of six years. Participants were examined from two to nine times, with an average of 6.6 times, resulting in 576 SST-DTI datasets. Tract-Based Spatial Statistics (TBSS) was used to create a mean FA skeleton, representing the centers of all with matter fiber tracts common to the group. Data were analyzed using linear mixed models. Here we provide three effect size maps i.e. unthresholded t-maps, displaying the association between logarithm-transformed SSRT (SSRTlog) and FA, FA-by-age and FA-by-age2, across the white matter skeleton.Communities: developmental
Related article: http://doi.org/10.1016/j.neuroimage.2020.117105
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