Brain structure associations with phonemic and semantic fluency in typically-developing children

Description: Verbal fluency is the ability to retrieve lexical knowledge quickly and efficiently and develops during childhood and adolescence. Few studies have investigated associations between verbal fluency performance and brain structural variation in children. Here we examined associations of verbal fluency performance with structural measures of frontal and temporal language-related brain regions and their connections. Seventy-three typically-developing children aged 7-13 years completed a phonemic and a semantic fluency task and underwent diffusion-weighted imaging, which was analyzed using tract-based spatial statistics (TBSS). The unthresholded t-maps of the association of semantic (categorical) fluency or phonemic (letter) fluency with FA, controlling for age and sex, as well as the TFCE corrected 1-p map for semantic fluency have been uploaded.

Communities: developmental

Related article: http://doi.org/10.1016/j.dcn.2021.100982