Are Brain Responses to Emotion a Reliable Endophenotype of Schizophrenia? An Image-Based Functional Magnetic Resonance Imaging Meta-analysis

Description: This collection describes the results of an image-based meta-analysis of brain activation to negative emotional stimuli in people at enhanced risk of schizophrenia ("at-risk"). The analyses include 17 fMRI studies for a total of 677 at-risk individuals and 805 healthy controls. Unthresholded group-level T-maps from individual studies were used as inputs to separately perform frequentist and Bayesian meta-analyses by implementing a random effect model. For frequentist analysis, we employed the software Seed-based d Mapping (SDM) v6.21. For Bayesian analysis, we used BayesFactorFMRI toolbox.

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Field	Value
Compact Identifier	https://identifiers.org/neurovault.collection:12180
Add Date	Jan. 17, 2022, 12:15 p.m.
Contributors
Related article DOI	10.1016/j.biopsych.2022.06.013
Related article authors	Anna M. Fiorito, André Aleman, Giuseppe Blasi, Josiane Bourque, Hengyi Cao, Raymond C.K. Chan, Asadur Chowdury, Patricia Conrod, Vaibhav A. Diwadkar, Vina M. Goghari, Salvador Guinjoan, Raquel E. Gur, Ruben C. Gur, Jun Soo Kwon, Johannes Lieslehto, Paulina B. Lukow, Andreas Meyer-Lindenberg, Gemma Modinos, Tiziana Quarto, Michael J. Spilka, Venkataram Shivakumar, Ganesan Venkatasubramanian, Mirta Villarreal, Yi Wang, Daniel H. Wolf, Je-Yeon Yun, Eric Fakra and Guillaume Sescousse

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